There is no cure for allergies, but there are several types of medicines available — both over-the-counter and prescription — to help ease annoying symptoms like congestion and runny nose. These include antihistamines, decongestants, combination medicines, corticosteroids and others. Allergy shots, which gradually increase your ability to tolerate allergens, are also available.
Antihistamines
Antihistamines have been used for years to treat allergy symptoms. They can be taken as pills, liquid, nasal spray or eye drops. Over-the-counter antihistamine eye drops can relieve red itchy eyes, while nasal sprays can be used to treat the symptoms of seasonal or year-round allergies.
Examples of antihistamines include:
• Over-the-counter: Benadryl, Claritin, Chlor-Trimeton, Dimetane, Zyrtec, and Tavist. Ocu-Hist is an OTC eye drop.
• Prescription: Clarinex and Allegra. Astelin is a prescription nasal spray. Eye drops include Emadine and Livostin.
How Do Antihistamines Work?
When you are exposed to an allergen — like ragweed pollen — it triggers your immune system to go into action. Immune system cells known as “mast cells” release a substance called histamine, which attaches to receptors in blood vessels causing them to enlarge. Histamine also binds to other receptors causing redness, swelling, itching and changes in secretions. By blocking histamine receptors, antihistamines prevent these symptoms.
What Are the Side Effects?
Many over-the-counter antihistamines cause drowsiness. Non-sedating antihistamines are available by prescription.
Decongestants
Decongestants relieve congestion and are often prescribed along with antihistamines. They come in nasal spray, eye drop, liquid or pill form. Nasal spray and eye drop decongestants can be used for only a few days, since long-term use can actually make symptoms worse. Pills and liquid decongestants may be taken longer safely.
Some examples of decongestants include:
• Over-the-counter: Zytec-D, Sudafed tablets or liquid, Neo-Synephrine and Afrin nasal sprays, and Visine eye drops.
• Prescription: Prescription decongestants include drugs like Claritin-D and Allegra-D that combine a decongestant with another allergy medicine.
How Do Decongestants Work?
During an allergic reaction, tissues in your nose swell in response to contact with the allergen. That swelling produces fluid and mucous. Blood vessels in the eyes also swell, causing redness. Decongestants shrink swollen nasal tissues and blood vessels to relieve the symptoms of nasal swelling, congestion, mucous secretion and redness.
What Are the Side Effects?
Decongestants may raise blood pressure, so they are not recommended for people who have blood pressure problems or glaucoma. They may also cause insomnia or irritability and restrict urinary flow.
Combination Medicines
Some allergy medicines contain both an antihistamine and a decongestant to relieve multiple symptoms. There are also other combinations, such as those between an allergy medicine and asthma medicine and an antihistamine eye drop with a mast cell stabilizer drug (see below).
Some examples of combination medicines include:
• Over-the-counter: Zyrtec-D , Benadryl Allergy and Sinus, Tylenol Allergy and Sinus.
• Prescription: Allegra-D, Claritin-D, and Semprex-D for nasal allergies. Naphcon, Vasocon, Zaditor, Patanol and Optivar for allergic conjunctivitis.
Steroids
Steroids, known medically as corticosteroids, reduce inflammation associated with allergies. They prevent and treat nasal stuffiness, sneezing, and itchy, runny nose due to seasonal or year-round allergies. They can also decrease inflammation and swelling from other types of allergic reactions.
Steroids are available as pills, for serious allergies or asthma, inhalers, for asthma, nasal sprays, for seasonal or year-round allergies, creams, for skin allergies or as an eye drop, for allergic conjunctivitis. Your doctor may prescribe a steroid in addition to other allergy medications. The drugs are highly effective, but they must be taken daily to be of benefit — even when you aren’t feeling symptoms. In addition, it may take one to two weeks before the full effect of the medicine can be felt.
Some steroids include:
• Nasal steroids: Beconase, Flonase, Nasocort, Nasonex, Rhinocort , and Veramyst used to treat nasal allergy symptoms.
• Inhaled steroids: Azmacort, Beclovent, Flovent, and Pulmicort used to treat asthma. Advair is an inhaled drug that combines a steroid with another drug to treat asthma. Inhaled steroids are available only with a prescription.
• Eye drops: Alrex and Dexamethasone
• Oral steroids: Deltasone, also called prednisone.
What Are the Side Effects?
Steroids have many potential side effects, especially when given orally and for a long period of time.
Side effects with short-term use include:
• Weight gain
• Fluid retention
• High blood pressure
Side effects with long-term use include:
• Growth suppression
• Diabetes
• Cataracts of the eyes
• Bone thinning osteoporosis
• Muscle weakness